Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.77 |
| ▸ | CA2 | P00918 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761771 | 0.96 | CA1 (0.70) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL11255125 | 0.89 | MAPT (0.64) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL17602252 | 0.88 | MAOB (0.74) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL11253865 | 0.88 | MAPT (0.74) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL18415526 | 0.88 | CA1 (1.00) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL978502 | 0.88 | RAB9A (0.71) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL15755152 | 0.86 | FFAR1 (0.69) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL15761770 | 0.86 | HIF1A (0.65) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL9335386 | 0.85 | RAB9A (0.60) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL6162284 | 0.85 | SMN1; SMN2 (0.79) | MAPTMEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2024-12-05 | — | — | US | disclosed |
| CN-118302401-A | Dual inhibitors of histone deacetylase 6 and heat shock protein 90 | 台北医学大学 | 2024-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | HSP90AB1, HDAC6, HSP90AB2P | CA1 2611/4885CA2 2289/4885MAPT 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.