Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 10/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29245338 | 1.00 | PRKAA2 (0.42) | PRKAA2GPR119PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL25190399 | 0.87 | HRH3 (0.45) | RAF1BRAFEPHX2USP30 | |
| SCHEMBL31362178 | 0.86 | USP30 (0.48) | PRKAA2GPR119RAF1BRAFEPHX2 | |
| SCHEMBL25245422 | 0.86 | USP30 (0.48) | PRKAA2GPR119RAF1BRAFEPHX2 | |
| SCHEMBL25282936 | 0.82 | GPR119 (0.42) | PRKAA2GPR119PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL29245342 | 0.79 | USP30 (0.37) | GPR119USP30 | |
| SCHEMBL29245343 | 0.79 | USP30 (0.37) | GPR119USP30 | |
| SCHEMBL25607156 | 0.79 | PRKAA2 (0.46) | PRKAA2GPR119PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL25288882 | 0.78 | PRKAA2 (0.41) | PRKAA2GPR119PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL25200137 | 0.77 | PRKAA2 (0.57) | PRKAA2GPR119PRKAB2PRKAG1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019532-A | Azetidine and pyrrolidine PARP1 inhibitors and uses thereof | 新特拉有限公司 | 2024-05-10 | — | — | CN | disclosed |