Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067540 | 1.00 | KDM1A (0.51) | KDM1AMAOAKCNH2KDM1BMAOB | |
| SCHEMBL29245879 | 0.86 | GLA (0.40) | — | |
| SCHEMBL31067621 | 0.86 | GLA (0.40) | — | |
| Hydrochloric Acid SCHEMBL17002961 | 0.76 | KDM1A (0.59) | KDM1AMAOAKCNH2KDM1BMAOB | |
| Hydrochloric Acid SCHEMBL17002963 | 0.76 | KDM1A (0.59) | KDM1AMAOAKCNH2KDM1BMAOB | |
| SCHEMBL2306460 | 0.74 | KDR (0.49) | — | |
| SCHEMBL4827923 | 0.74 | HPGD (0.70) | — | |
| SCHEMBL9615374 | 0.71 | RAB9A (0.58) | — | |
| SCHEMBL28928511 | 0.71 | LOXL2 (0.44) | — | |
| SCHEMBL29245888 | 0.70 | HPGD (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |