Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974768 | 1.00 | HTR6 (0.59) | HTR6AKR1C3AKR1C1HTR1ADRD2 | |
| SCHEMBL13051118 | 0.89 | HTR6 (0.52) | HTR6AKR1C3AKR1C1HTR1ADRD2 | |
| SCHEMBL30295250 | 0.86 | HTR6 (0.61) | HTR6CA1CA2CA9 | |
| SCHEMBL1895249 | 0.86 | HTR6 (0.61) | HTR6CA1CA2CA9 | |
| SCHEMBL29651100 | 0.82 | HTR6 (0.64) | HTR6AKR1C3AKR1C1HTR1ADRD2 | |
| SCHEMBL1996382 | 0.82 | HTR6 (0.64) | HTR6AKR1C3AKR1C1HTR1ADRD2 | |
| SCHEMBL29247631 | 0.78 | HTR6 (0.57) | HTR6AKR1C3AKR1C1HTR1ADRD2 | |
| SCHEMBL3893764 | 0.78 | HTR6 (0.73) | HTR6HTR1ADRD2HTR7HTR1D | |
| SCHEMBL29247793 | 0.77 | HTR6 (0.56) | HTR6HTR1ADRD2HTR7LMNA | |
| SCHEMBL30372616 | 0.77 | HTR6 (0.56) | HTR6HTR1ADRD2HTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |