Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996382 | 1.00 | HTR6 (0.64) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL29460860 | 0.87 | KDM4E (0.68) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL517434 | 0.87 | KDM4E (0.68) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL9587637 | 0.85 | AKR1C3 (0.52) | HTR6AKR1C3AKR1C1CA12CA1 | |
| SCHEMBL19737423 | 0.85 | HTR6 (0.59) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL4334765 | 0.85 | HTR6 (0.52) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL1015250 | 0.85 | HTR6 (0.58) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL19737553 | 0.82 | HTR6 (0.49) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL13051118 | 0.82 | HTR6 (0.52) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 | |
| SCHEMBL30974768 | 0.82 | HTR6 (0.59) | HTR6AKR1C3AKR1C1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114555585-A | HPK1 inhibitors and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3994133-A1 | HPK1 INHIBITORS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2022-05-11 | — | — | EP | disclosed |