Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360938 | 0.77 | — | — | |
| SCHEMBL24425916 | 0.74 | DYRK1A (0.72) | DYRK1AFFAR1PPARDPIK3CAMTOR | |
| SCHEMBL28172473 | 0.72 | DYRK1A (0.60) | DYRK1AFFAR1PPARDPIK3CAMTOR | |
| SCHEMBL28357177 | 0.71 | MAPK14 (0.49) | DYRK1APIK3CAMTORNPC1RAB9A | |
| SCHEMBL28360929 | 0.71 | QPCT (0.47) | NPC1RAB9ASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL3424519 | 0.71 | DYRK1A (0.49) | DYRK1ANPC1RAB9ASMN1; SMN2PDE4A | |
| SCHEMBL29689417 | 0.70 | DYRK1A (0.62) | DYRK1AFFAR1PPARDPIK3CAMTOR | |
| SCHEMBL150096 | 0.67 | MAOB (0.32) | NPC1RAB9A | |
| SCHEMBL1798498 | 0.67 | DYRK1A (0.49) | DYRK1APIK3CAMTORNPC1RAB9A | |
| SCHEMBL28356989 | 0.67 | MAPK14 (0.39) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317965-A | Adenosine receptor antagonists | 交信医药研发公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118317965-A | Adenosine receptor antagonists | 交信医药研发公司 | 2024-07-09 | — | — | CN | disclosed |