Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 4/20 | 0.36 |
| ▸ | CDK8 | P49336 | 4/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421046 | 0.89 | CD274 (0.38) | ADAMTS4CCNCCDK8CD274GRIN1 | |
| SCHEMBL21612897 | 0.75 | HTT (0.40) | CD274CYP1A2CYP2C9 | |
| SCHEMBL25027328 | 0.74 | KDM4E (0.39) | ACHE | |
| SCHEMBL25027331 | 0.73 | KDM4E (0.36) | ACHE | |
| SCHEMBL25348004 | 0.69 | GPR119 (0.37) | CCNCCDK8CD274MKNK1MKNK2 | |
| SCHEMBL30519933 | 0.69 | GPR119 (0.37) | CCNCCDK8CD274MKNK1MKNK2 | |
| SCHEMBL25754081 | 0.69 | EP300 (0.48) | CCNCCDK8NAMPTMKNK1MKNK2 | |
| SCHEMBL31413896 | 0.69 | JAK2 (0.33) | CYP2C9 | |
| SCHEMBL26071338 | 0.68 | ACVR2A (0.41) | — | |
| SCHEMBL12516034 | 0.67 | EPHB4 (0.50) | CCNCCDK8NAMPTMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317774-A | Pharmaceutical compositions comprising quinazoline compounds | 安斯泰来制药株式会社 | 2024-07-09 | — | — | CN | disclosed |