Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 11/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420871 | 0.88 | MEN1 (0.39) | MEN1MAPTTHRBMAPK1HTT | |
| SCHEMBL29036155 | 0.72 | PRMT6 (0.34) | P2RX1P2RX4 | |
| SCHEMBL19337001 | 0.71 | KDM4E (0.35) | MAPTHTTSMN1; SMN2P2RX1P2RX4 | |
| SCHEMBL29036146 | 0.69 | BCHE (0.34) | CES1 | |
| SCHEMBL30534441 | 0.69 | BCHE (0.34) | CES1 | |
| SCHEMBL31575079 | 0.65 | P2RX4 (0.34) | P2RX1P2RX4 | |
| SCHEMBL29036163 | 0.65 | SLC6A2 (0.31) | — | |
| SCHEMBL28896942 | 0.65 | MAPT (0.40) | MEN1MAPTTHRBMAPK1KMT2A | |
| SCHEMBL29036162 | 0.63 | ALDH1A1 (0.39) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL30534482 | 0.63 | ALDH1A1 (0.39) | MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165009-A | 6-Aryl-1, 4-benzoxazine-imidazoline (thio) ketone compound and preparation method and application thereof | 湖南科技大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118165009-A | 6-Aryl-1, 4-benzoxazine-imidazoline (thio) ketone compound and preparation method and application thereof | 湖南科技大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-118165009-A | 6-Aryl-1, 4-benzoxazine-imidazoline (thio) ketone compound and preparation method and application thereof | 湖南科技大学 | 2024-06-11 | — | — | CN | disclosed |