Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 8/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 7/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.33 |
| ▸ | INSR | P06213 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.32 |
| ▸ | IKBKB | O14920 | 5/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26679894 | 0.85 | ENPP1 (0.56) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL29691468 | 0.85 | ENPP1 (0.56) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL26680004 | 0.83 | ENPP1 (0.40) | ENPP1ENPP3CHUKCAMKK2INSR | |
| SCHEMBL29691648 | 0.82 | CA12 (0.51) | ENPP1ENPP3NEK1 | |
| SCHEMBL24600500 | 0.82 | CA12 (0.51) | ENPP1ENPP3NEK1 | |
| SCHEMBL29248789 | 0.80 | CAMKK2 (0.35) | ENPP1ENPP3CHUKCAMKK2INSR | |
| SCHEMBL26679830 | 0.80 | ENPP1 (0.38) | ENPP1ENPP3CHUKCAMKK2INSR | |
| SCHEMBL29248809 | 0.80 | ENPP1 (0.43) | ENPP1ENPP3CHUKCAMKK2INSR | |
| SCHEMBL29691523 | 0.77 | GRM2 (0.46) | — | |
| SCHEMBL24600607 | 0.77 | GRM2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |