Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 4/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 14/20 | 0.41 |
| ▸ | IKBKB | O14920 | 11/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.40 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29248817 | 0.88 | NUDT1 (0.41) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL29248812 | 0.84 | ENPP1 (0.42) | ENPP1CHUKIKBKBROCK1INSR | |
| SCHEMBL29691620 | 0.83 | ENPP1 (0.56) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL24600558 | 0.83 | ENPP1 (0.56) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL26679935 | 0.81 | IKBKB (0.46) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL29248776 | 0.80 | CHUK (0.43) | CHUKIKBKBROCK1INSRMAPK8 | |
| SCHEMBL29248792 | 0.80 | ENPP1 (0.44) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL29691621 | 0.79 | CA12 (0.53) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL24600502 | 0.79 | CA12 (0.53) | ENPP1ENPP3CHUKIKBKBROCK1 | |
| SCHEMBL24600501 | 0.78 | CCNK (0.46) | ENPP1ENPP3CHUKIKBKBROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |