Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.39 |
| ▸ | CHUK | O15111 | 5/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 3/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29691558 | 0.99 | IKBKB (0.39) | IKBKBCHUKROCK1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL26679839 | 0.99 | IKBKB (0.39) | IKBKBCHUKROCK1CCNKCDK12 | |
| SCHEMBL24600499 | 0.90 | BTK (0.40) | IKBKBCHUKROCK1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL26679831 | 0.89 | BTK (0.39) | IKBKBCHUKROCK1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL29691615 | 0.89 | BTK (0.39) | IKBKBCHUKROCK1CCNKCDK12 | |
| SCHEMBL24600593 | 0.85 | PDE3B (0.34) | IKBKBCHUKROCK1CCNKCDK12 | |
| SCHEMBL24600592 | 0.84 | ENPP1 (0.46) | IKBKBCHUKROCK1CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL26679908 | 0.83 | ENPP1 (0.48) | IKBKBCHUKROCK1CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL26679901 | 0.83 | CDK9 (0.37) | IKBKBCHUKROCK1PDE3BPDE3A | |
| SCHEMBL24600503 | 0.79 | PRKCI (0.43) | IKBKBCHUKROCK1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |