Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.34 |
| ▸ | IKBKB | O14920 | 5/20 | 0.34 |
| ▸ | CHUK | O15111 | 5/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.34 |
| ▸ | CDK9 | P50750 | 5/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29248806 | 0.85 | IKBKB (0.39) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL29691558 | 0.84 | IKBKB (0.39) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL26679839 | 0.84 | IKBKB (0.39) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| SCHEMBL24600592 | 0.84 | ENPP1 (0.46) | IKBKBCHUKROCK1CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL26679908 | 0.83 | ENPP1 (0.48) | IKBKBCHUKROCK1CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL26679901 | 0.83 | CDK9 (0.37) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| SCHEMBL24600623 | 0.80 | NUDT1 (0.40) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| SCHEMBL24600499 | 0.78 | BTK (0.40) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL29691615 | 0.77 | BTK (0.39) | PDE3BPDE3ANUDT1IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL26679831 | 0.77 | BTK (0.39) | PDE3BPDE3ANUDT1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |