Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845935 | 0.83 | HTT (0.56) | ALDH1A1MAPTTSHRHTTKDM4E | |
| SCHEMBL29249633 | 0.80 | PARP1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15500822 | 0.79 | RXFP1 (0.51) | ALDH1A1MAPTTSHRKDM4ERXFP1 | |
| SCHEMBL30264706 | 0.76 | PDE10A (0.52) | PDE10AEGFRALKRETKDR | |
| SCHEMBL24728976 | 0.75 | LMNA (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30647543 | 0.75 | LMNA (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21756245 | 0.74 | EGFR (0.50) | CA1CA2CA9PDE10AALDH1A1 | |
| SCHEMBL23733197 | 0.74 | HTT (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10091835 | 0.73 | CA12 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7806458 | 0.73 | RAF1 (0.52) | PARP1EGFRERBB2ALKRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836013-A | Radiotracer and therapeutic agents that bind to Fibroblast Activation Protein (FAP) | 蓝地诊断有限公司 | 2024-04-05 | — | — | CN | disclosed |