Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690080 | 0.85 | DHODH (0.54) | HTTTSHRMAPTKDM4EGAA | |
| SCHEMBL15414841 | 0.83 | MEN1 (0.59) | HTTTSHRMAPTKDM4EHPGD | |
| SCHEMBL10091835 | 0.79 | CA12 (0.49) | HTTTSHRGABRPGABRDGABRA1 | |
| SCHEMBL9907354 | 0.75 | PAX8 (0.48) | HTTTSHRMAPTKDM4EHPGD | |
| SCHEMBL29249689 | 0.74 | GABRP (0.45) | HTTTSHRGABRPGABRDGABRA1 | |
| SCHEMBL24728976 | 0.74 | LMNA (0.52) | HTTTSHRGABRPGABRDGABRA1 | |
| SCHEMBL30647543 | 0.74 | LMNA (0.52) | HTTTSHRGABRPGABRDGABRA1 | |
| SCHEMBL2012625 | 0.74 | PLA2G2A (0.50) | HTTTSHRCYP3A4MAPTKDM4E | |
| SCHEMBL9907355 | 0.73 | PAX8 (0.49) | HTTTSHRMAPTKDM4EHPGD | |
| SCHEMBL5963018 | 0.72 | CYP3A4 (0.47) | HTTTSHRGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155292-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP) - TARGETED ANTIFIBROTIC THERAPY | LOW PHILIP STEWART (US) | 2021-08-05 | — | — | WO | disclosed |