Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 3/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.47 |
| ▸ | MERTK | Q12866 | 3/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 10/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537792 | 1.00 | CCNT1 (0.50) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL26619221 | 0.91 | CCNE2 (0.48) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL29537557 | 0.91 | CCNE2 (0.48) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL29065177 | 0.89 | CDK2 (0.46) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL29508046 | 0.89 | CDK2 (0.46) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL24393262 | 0.86 | TYRO3 (0.51) | AXLTYRO3MERTKDDR2CTSC | |
| SCHEMBL29537423 | 0.86 | TYRO3 (0.51) | AXLTYRO3MERTKDDR2CTSC | |
| SCHEMBL29507923 | 0.85 | CDK2 (0.49) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL29508053 | 0.85 | CDK2 (0.49) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL29538078 | 0.85 | CDK2 (0.50) | CCNT1CCNE2CCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |