Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 5/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.42 |
| ▸ | AXL | P30530 | 3/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619221 | 1.00 | CCNE2 (0.48) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29537792 | 0.91 | CCNT1 (0.50) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29250640 | 0.91 | CCNT1 (0.50) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29508046 | 0.91 | CDK2 (0.46) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29065177 | 0.91 | CDK2 (0.46) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29538078 | 0.91 | CDK2 (0.50) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29507923 | 0.88 | CDK2 (0.49) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29250654 | 0.88 | LRRK2 (0.40) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29537939 | 0.88 | LRRK2 (0.40) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL29508122 | 0.87 | CDK2 (0.48) | CCNE2CCNE1CDK2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923392-A | Salt and crystal forms of an epidermal growth factor receptor inhibitor | 缆图药品公司 | 2025-05-02 | — | — | CN | disclosed |
| EP-4519254-A1 | SALT AND CRYSTAL FORMS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR | Blueprint Medicines Corporation (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215431-A1 | SALT AND CRYSTAL FORMS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR | BLUEPRINT MEDICINES CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| EP-4237418-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS, AND MEDICINAL APPLICATIONS THEREOF | Blueprint Medicines Corporation (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |
| WO-2022094354-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS, AND MEDICINAL APPLICATIONS THEREOF | LENGO THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |