Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802227 | 0.77 | KDM4E (0.59) | KDM4ECA1CA2THRBMAOA | |
| SCHEMBL4261482 | 0.74 | CA1 (1.00) | KDM4ECA1CA2THRBMAOA | |
| SCHEMBL8752350 | 0.74 | KDM4E (1.00) | KDM4ECA1CA2THRBMAOA | |
| SCHEMBL1423181 | 0.74 | KMT2A (0.65) | KDM4ECA1CA2MAOAALDH1A1 | |
| SCHEMBL4696277 | 0.74 | MAOA (0.90) | KDM4ECA1CA2MAOAALDH1A1 | |
| Xanthone SCHEMBL29398266 | 0.74 | MAOA (1.00) | KDM4EMAOAALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL41161 | 0.74 | MAOA (1.00) | KDM4EMAOAALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL29358061 | 0.74 | MAOA (1.00) | KDM4EMAOAALDH1A1GLACYP3A4 | |
| Xanthone SCHEMBL2354794 | 0.74 | MAOA (1.00) | KDM4EMAOAALDH1A1GLACYP3A4 | |
| SCHEMBL7483002 | 0.73 | GAA (0.69) | KDM4EMAOAALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290443-A | Chromone heterocyclic compound, and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-05 | — | — | CN | claimed |
| CN-118290443-A | Chromone heterocyclic compound, and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-05 | — | — | CN | disclosed |