Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952496 | 0.95 | TSHR (0.41) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL28289680 | 0.94 | TSHR (0.40) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL486276 | 0.90 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL2491695 | 0.78 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL584640 | 0.76 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL27913695 | 0.73 | TSHR (0.50) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL3446806 | 0.72 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL7766210 | 0.68 | TSHR (0.47) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL28136239 | 0.68 | TSHR (0.53) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL28520104 | 0.67 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290672-A | Acrylic ester graft copolymer with core-shell structure, preparation method thereof and application thereof as impact modifier | 中化学科学技术研究有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290673-A | Core-shell ASA copolymer, preparation method thereof and application thereof as impact modifier | 中化学科学技术研究有限公司 | 2024-07-05 | — | — | CN | disclosed |