Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394880 | 0.90 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL4393987 | 0.88 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3748229 | 0.85 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL4357212 | 0.85 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11143543 | 0.83 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL21879730 | 0.83 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27913695 | 0.75 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL584640 | 0.75 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL486276 | 0.74 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL705156 | 0.73 | ALDH1A1 (0.38) | TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786464-B1 | A method for manufacturing acryloxypropylsilane | CHISSO CORP (JP) | 2001-05-30 | — | — | EP | claimed |