SCHEMBL2491695

SCHEMBL2491695

C=C(C)C(=O)O[SiH](CCCC)C(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
THRB P10828 1/20 0.34
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1490337 0.90 THRB (0.36) TSHRTHRBALDH1A1
SCHEMBL27764596 0.83 THRB (0.38) TSHRTHRBALDH1A1
SCHEMBL584057 0.76 ALDH1A1 (0.38) TSHRTHRBALDH1A1
SCHEMBL27926533 0.75 THRB (0.39) TSHRTHRBALDH1A1
SCHEMBL1846279 0.75 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL27952496 0.74 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL28289680 0.73 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL1274035 0.72 TSHR (0.33) TSHRTHRBALDH1A1
SCHEMBL3898609 0.70 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL10430813 0.69 TSHR (0.36) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
EP-4085100-A1 CHEMICAL RESISTANT POLYCARBONATE BLEND COMPOSITIONS Covestro LLC (US) 2022-11-09 EP disclosed
EP-3887449-A1 SICOPC BLEND CONTAINING PHOSPHAZENE AND SILICONE/ACRYLATE IMPACT MODIFIER Covestro Intellectual Property GmbH & Co. KG (DE) 2021-10-06 EP disclosed
WO-2021138113-A1 CHEMICAL RESISTANT POLYCARBONATE BLEND COMPOSITIONS COVESTRO LLC (US) 2021-07-08 WO disclosed
WO-2021105008-A1 FLAME-RESISTANT POLYCARBONATE-POLYESTER BLEND COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-03 WO disclosed
WO-2021065721-A1 WATER REPELLENCY-IMPARTING AGENT, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF テクノUMG株式会社 2021-04-08 WO disclosed
EP-3728468-A1 POLYCARBONATE COMPOSITION HAVING GOOD LEVEL OF NON-FLAMMABILITY Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
WO-2020108922-A1 SICOPC BLEND CONTAINING PHOSPHAZENE AND SILICONE/ACRYLATE IMPACT MODIFIER COVESTRO DEUTSCHLAND AG (DE) 2020-06-04 WO disclosed
CN-105636997-A Polyorganosiloxane-containing graft copolymer, resin composition, molded body, sliding property improver, and sliding member MITSUBISHI RAYON CO 2016-06-01 CN disclosed
CN-1061067-C Impact resistant resin composition GEN ELECTRIC (US) 2001-01-24 CN disclosed
WO-2000039210-A1 POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2000-07-06 WO disclosed
EP-0663425-B1 Impact resistant copolycarbonate composition GEN ELECTRIC (US) 2000-05-03 EP disclosed
US-5602201-A CONTAINING AROMATIC POLYCARBONATE COPOLYMER, ACRYLONITRILE-STYRENE COPOLYMER, RUBBER COMPLEX GRAFT POLYMER HAVING POLYSILOXANE AND POLYALKYL ACRYLATE UNITS GENERAL ELECTRIC COMPANY (US) 1997-02-11 US disclosed
CN-1110695-A Impact resistant resin composition GEN ELECTRIC (US) 1995-10-25 CN disclosed
EP-0663425-A2 Impact resistant copolycarbonate composition GENERAL ELECTRIC COMPANY (US) 1995-07-19 EP disclosed
EP-0480426-A1 Polyarylene sulfide resin compositions MITSUBISHI RAYON CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0468462-A2 Resin compositions excellent in impact resistance and heat stability MITSUBISHI RAYON CO., LTD. (JP) 1992-01-29 EP disclosed
EP-0369376-A2 Flame retardant polyphenylene ether resin composition MITSUBISHI RAYON CO., LTD. (JP) 1990-05-23 EP disclosed
EP-0307963-A2 Polycarbonate resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-22 EP disclosed