Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 9/20 | 0.34 |
| ▸ | EGFR | P00533 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086539 | 1.00 | LTA4H (0.42) | LTA4HKCNH2S1PR3BTKEGFR | |
| SCHEMBL31086390 | 1.00 | LTA4H (0.42) | LTA4HKCNH2S1PR3BTKEGFR | |
| SCHEMBL29254750 | 1.00 | LTA4H (0.42) | LTA4HKCNH2S1PR3BTKEGFR | |
| SCHEMBL29254976 | 0.94 | LTA4H (0.40) | LTA4HKCNH2S1PR3BTKEGFR | |
| SCHEMBL29255181 | 0.84 | LTA4H (0.47) | LTA4HKCNH2BTKEGFR | |
| SCHEMBL29255111 | 0.83 | LTA4H (0.47) | LTA4HKCNH2BTK | |
| SCHEMBL29255153 | 0.81 | LTA4H (0.44) | LTA4HKCNH2BTKEGFR | |
| SCHEMBL31086357 | 0.79 | LTA4H (0.45) | LTA4HKCNH2BTKEGFR | |
| SCHEMBL24664199 | 0.77 | LTA4H (0.46) | LTA4HKCNH2S1PR3BTKPPARG | |
| SCHEMBL30006114 | 0.77 | LTA4H (0.46) | LTA4HKCNH2S1PR3BTKPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |