Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086357 | 0.93 | LTA4H (0.45) | LTA4HKCNH2S1PR5BTK | |
| SCHEMBL29255181 | 0.92 | LTA4H (0.47) | LTA4HKCNH2S1PR5BTK | |
| SCHEMBL29255153 | 0.91 | LTA4H (0.44) | LTA4HKCNH2S1PR1BTK | |
| SCHEMBL31086539 | 0.83 | LTA4H (0.42) | LTA4HKCNH2BTK | |
| SCHEMBL29254750 | 0.83 | LTA4H (0.42) | LTA4HKCNH2BTK | |
| SCHEMBL31086390 | 0.83 | LTA4H (0.42) | LTA4HKCNH2BTK | |
| SCHEMBL29254754 | 0.83 | LTA4H (0.42) | LTA4HKCNH2BTK | |
| SCHEMBL31086419 | 0.82 | LTA4H (0.56) | LTA4HKCNH2BTK | |
| SCHEMBL29254876 | 0.82 | LTA4H (0.56) | LTA4HKCNH2BTK | |
| SCHEMBL19439496 | 0.79 | LTA4H (0.65) | LTA4HKCNH2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |