Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | CDC25B | P30305 | 6/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | CDC25A | P30304 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16232045 | 0.82 | ATM (0.62) | ALDH1A1TSHRATMSYK | |
| SCHEMBL3331695 | 0.81 | ACE (0.56) | PTPN1CDC25BPTPN2CDC25AMME | |
| SCHEMBL304588 | 0.81 | ACE (0.56) | PTPN1CDC25BPTPN2CDC25AMME | |
| SCHEMBL756405 | 0.80 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL10132030 | 0.80 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL18183914 | 0.80 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL18681590 | 0.80 | CYP19A1 (0.44) | CYP19A1ATMHDAC1PTPN1CDC25B | |
| SCHEMBL19701644 | 0.78 | PTPN1 (0.43) | ALDH1A1LMNAHDAC1PTPN1CDC25B | |
| SCHEMBL1912621 | 0.76 | CTSS (0.55) | TSHRATMSYKMME | |
| SCHEMBL8336513 | 0.76 | PPARA (0.57) | TSHRATMSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |