Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | CDC25B | P30305 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19701642 | 0.91 | CYP19A1 (0.43) | MMEALDH1A1LMNAHDAC1 | |
| SCHEMBL10132030 | 0.88 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL756405 | 0.88 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL18183914 | 0.88 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL3331695 | 0.87 | ACE (0.56) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL304588 | 0.87 | ACE (0.56) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL19697731 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHDAC1 | |
| SCHEMBL18681590 | 0.80 | CYP19A1 (0.44) | PTPN1CDC25BPTPN2CDC25AACE | |
| SCHEMBL13046915 | 0.79 | PTPN1 (0.50) | PTPN1CDC25BPTPN2CDC25ACTSS | |
| SCHEMBL3784417 | 0.79 | PPARA (0.52) | PTPN1CDC25BPTPN2CDC25AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355689-A1 | HEPATITIS C VIRUS INHIBITOR | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355689-A1 | HEPATITIS C VIRUS INHIBITOR | HAVCR2, LIPC, PYGL | PTPN1 1848/4885CDC25B 1024/4885PTPN2 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.