Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254756 | 0.94 | LMNA (0.42) | PPARGLMNAPTGER4PTGER2LTA4H | |
| SCHEMBL29255006 | 0.89 | LTA4H (0.44) | PPARGLMNAPTGER4PTGER2LTA4H | |
| SCHEMBL31086456 | 0.89 | LTA4H (0.44) | PPARGLMNAPTGER4PTGER2LTA4H | |
| SCHEMBL31086470 | 0.88 | PPARG (0.39) | PPARGPTGER4PTGER2LTA4HKCNH2 | |
| SCHEMBL29255220 | 0.88 | PPARG (0.39) | PPARGPTGER4PTGER2LTA4HKCNH2 | |
| SCHEMBL29255445 | 0.83 | LTA4H (0.41) | PPARGPTGER4PTGER2LTA4HKCNH2 | |
| SCHEMBL29254940 | 0.83 | PPARG (0.42) | PPARGLMNAPTGER4PTGER2LTA4H | |
| SCHEMBL29255278 | 0.83 | LTA4H (0.43) | PPARGLMNAPTGER4PTGER2LTA4H | |
| Hydrochloric Acid SCHEMBL29255051 | 0.83 | LTA4H (0.40) | PPARGPTGER4PTGER2LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL29255053 | 0.83 | LTA4H (0.41) | PPARGPTGER4PTGER2LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |