Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30402118 | 0.82 | RAB9A (0.54) | ALDH1A1LMNAPDCD1CD274NPC1 | |
| SCHEMBL29028437 | 0.82 | RAB9A (0.54) | ALDH1A1LMNAPDCD1CD274NPC1 | |
| SCHEMBL29028473 | 0.81 | PDCD1 (0.49) | ALDH1A1LMNAPDCD1CD274NPC1 | |
| SCHEMBL30402111 | 0.81 | PDCD1 (0.49) | ALDH1A1LMNAPDCD1CD274NPC1 | |
| SCHEMBL28629906 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30336483 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11920156 | 0.80 | RAB9A (0.67) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL485159 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29016786 | 0.75 | PDCD1 (0.42) | ALDH1A1LMNAPDCD1CD274 | |
| SCHEMBL30566761 | 0.74 | SMN1; SMN2 (0.69) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026947-A | Biphenyl substituted five-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-14 | — | — | CN | disclosed |