Ortho-Phthalaldehyde

Ortho-Phthalaldehyde

SCHEMBL29256362

NNC(N)=S.NNC(N)=S.O=Cc1ccccc1C=O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
LMNA P02545 1/20 0.56
THRB P10828 1/20 0.56
BLM P54132 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 2/20 0.43
PTGS2 P35354 1/20 0.43
GAA P10253 3/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 2/20 0.41
MAOB P27338 1/20 0.41
TP53 P04637 1/20 0.40
TYR P14679 1/20 0.40
TAS2R38 P59533 1/20 0.40
ERN1 O75460 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicyladehyde SCHEMBL28895807 0.88 TRIM24 (0.67) MEN1KMT2ALMNATHRBBLM
Salicyladehyde SCHEMBL28469026 0.87 TRIM24 (0.64) MEN1KMT2ALMNATHRBBLM
Thiosemicarbazide SCHEMBL27701286 0.82 KMT2A (0.38) MEN1KMT2ALMNATHRBBLM
Benzaldehyde SCHEMBL27964405 0.81 ALDH1A1 (0.58) KMT2ALMNAALDH1A1HSD17B10PTGS2
Thiosemicarbazide SCHEMBL11302646 0.79 PADI4 (0.48) MEN1KMT2ATHRBALDH1A1HSD17B10
Ortho-Phthalaldehyde SCHEMBL4953869 0.75 LMNA (1.00) MEN1KMT2ALMNATHRBBLM
Ortho-Phthalaldehyde SCHEMBL33393 0.75 LMNA (1.00) MEN1KMT2ALMNATHRBBLM
Ortho-Phthalaldehyde SCHEMBL29412642 0.75 LMNA (1.00) MEN1KMT2ALMNATHRBBLM
Salicyladehyde SCHEMBL28895950 0.74 TRIM24 (0.78) MEN1KMT2ALMNATHRBBLM
Thiourea SCHEMBL27964406 0.74 LMNA (0.50) MEN1KMT2ALMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084751-A Preparation process and application of phthalaldehyde Schiff base compound 酒泉亚佳化学有限公司 2024-05-28 CN disclosed