Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256556 | 1.00 | PYGL (0.46) | PYGLTRPV1IDO1HTR3EHTR3B | |
| SCHEMBL8443135 | 0.85 | AKR1C3 (0.48) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30173768 | 0.82 | AKR1C3 (0.46) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23782483 | 0.82 | AKR1C3 (0.46) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24956326 | 0.82 | HTR3E (0.47) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16957221 | 0.81 | IDO1 (0.41) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8511122 | 0.81 | IDO1 (0.45) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8511124 | 0.81 | IDO1 (0.45) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18704140 | 0.81 | NOTUM (0.39) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29208639 | 0.79 | AKR1C3 (0.52) | TRPV1KDRPDK1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340754-B | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-118340754-A | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2024-07-16 | — | — | CN | disclosed |