Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL10589847 | 0.97 | LMNA (0.44) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL193289 | 0.94 | ALDH1A1 (0.52) | TP53GMNNALDH1A1LMNATSHR | |
| Potassium Ion SCHEMBL28915686 | 0.94 | TP53 (0.46) | TP53GMNNALDH1A1LMNATSHR | |
| Zinc Ion SCHEMBL11039415 | 0.94 | TP53 (0.46) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL2384964 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL10885084 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL29271944 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL2384744 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL2383935 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR | |
| SCHEMBL4412723 | 0.92 | ALDH1A1 (0.50) | TP53GMNNALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146124-A | Sulfonate containing ester group, preparation process and application thereof | 苏州祺添新材料股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118146124-A | Sulfonate containing ester group, preparation process and application thereof | 苏州祺添新材料股份有限公司 | 2024-06-07 | — | — | CN | disclosed |