Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258119 | 1.00 | NAMPT (0.52) | NAMPTEPHX2ROCK2PPARGHSD17B13 | |
| SCHEMBL29258633 | 0.85 | EPHX2 (0.59) | NAMPTEPHX2ROCK2PPARGMAOB | |
| SCHEMBL29258630 | 0.85 | EPHX2 (0.59) | NAMPTEPHX2ROCK2PPARGMAOB | |
| SCHEMBL29258764 | 0.83 | NAMPT (0.59) | NAMPTHDAC1 | |
| SCHEMBL29258128 | 0.83 | NAMPT (0.64) | NAMPTEPHX2ROCK2PPARGHDAC3 | |
| SCHEMBL29258125 | 0.83 | NAMPT (0.64) | NAMPTEPHX2ROCK2PPARGHDAC3 | |
| SCHEMBL29258151 | 0.82 | NAMPT (0.77) | NAMPT | |
| SCHEMBL29258096 | 0.81 | ROCK2 (0.68) | NAMPTROCK2ROCK1CYP2C9 | |
| SCHEMBL29258099 | 0.81 | ROCK2 (0.68) | NAMPTROCK2ROCK1CYP2C9 | |
| SCHEMBL29258164 | 0.79 | NAMPT (0.57) | NAMPTEPHX2MAOBHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |