Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927217 | 1.00 | NAMPT (0.69) | NAMPTROCK2CYP19A1HDAC3HDAC1 | |
| SCHEMBL29258100 | 0.89 | NAMPT (0.69) | NAMPT | |
| SCHEMBL30927201 | 0.89 | NAMPT (0.69) | NAMPT | |
| SCHEMBL29258154 | 0.89 | NAMPT (0.68) | NAMPTHDAC1 | |
| SCHEMBL29258086 | 0.88 | NAMPT (0.71) | NAMPTHDAC1HDAC8 | |
| SCHEMBL30927236 | 0.86 | NAMPT (0.68) | NAMPT | |
| SCHEMBL30927229 | 0.86 | NAMPT (0.68) | NAMPT | |
| SCHEMBL29258286 | 0.86 | MEN1 (0.56) | NAMPTCYP19A1HDAC3HDAC1HDAC2 | |
| SCHEMBL30927215 | 0.86 | MEN1 (0.56) | NAMPTCYP19A1HDAC3HDAC1HDAC2 | |
| SCHEMBL29258225 | 0.86 | NAMPT (0.68) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |