SCHEMBL29258472

SCHEMBL29258472

COc1cccc(-c2nc(-c3nc(-c4cccc(OC)c4)c(-c4cccc(OC)c4)n3-c3ccc(F)cc3F)[nH]c2-c2cccc(OC)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 14/20 0.47
MAPK13 O15264 3/20 0.47
MAPK12 P53778 3/20 0.47
MAPK11 Q15759 3/20 0.47
RAF1 P04049 2/20 0.47
ALOX5 P09917 2/20 0.41
TEK Q02763 1/20 0.40
GCGR P47871 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
PDE10A Q9Y233 1/20 0.37
CSNK1D P48730 1/20 0.37
CSNK1E P49674 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29258832 0.91 MAPK14 (0.52) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28977872 0.89 MAPK14 (0.47) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL4651674 0.82 MAPK14 (0.51) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL6937515 0.79 MAPK14 (0.56) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL3454813 0.75 MAPK14 (0.71) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL6932540 0.74 MAPK14 (0.60) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL27925495 0.71 MGAM (0.47) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL15452429 0.70 MAPK14 (0.72) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL11212515 0.70 MAPK13 (0.76) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL10385875 0.70 NOX1 (0.52) MAPK14MAPK13MAPK12MAPK11RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112987496-B Photosensitive resin composition and transfer film using same 旭化成株式会社 2024-06-14 CN disclosed