SCHEMBL28977872

SCHEMBL28977872

COc1cccc(-c2nc(-c3nc(-c4cccc(OC)c4)c(-c4cccc(OC)c4)n3-c3ccc(F)c(F)c3F)[nH]c2-c2cccc(OC)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 15/20 0.47
MAPK13 O15264 1/20 0.47
RAF1 P04049 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
ALOX5 P09917 1/20 0.41
TEK Q02763 1/20 0.40
ADORA2A P29274 2/20 0.38
ADORA1 P30542 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29258832 0.89 MAPK14 (0.52) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL29258472 0.89 MAPK14 (0.47) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL4651674 0.82 MAPK14 (0.51) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL3454813 0.75 MAPK14 (0.71) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL6932540 0.74 MAPK14 (0.60) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL6937515 0.71 MAPK14 (0.56) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL15452429 0.70 MAPK14 (0.72) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL11212515 0.70 MAPK13 (0.76) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL7795648 0.70 MAPK14 (0.67) MAPK14MAPK13RAF1MAPK12MAPK11
SCHEMBL27925495 0.69 MGAM (0.47) MAPK14MAPK13RAF1MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115903380-A Photosensitive resin laminate 旭化成株式会社 2023-04-04 CN disclosed