SCHEMBL4651674

SCHEMBL4651674

COc1cccc(-c2nc(-c3nc(-c4cccc(OC)c4)c(-c4cccc(OC)c4)n3-c3ccccc3Cl)[nH]c2-c2cccc(OC)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 12/20 0.51
MAPK13 O15264 2/20 0.51
MAPK12 P53778 2/20 0.51
MAPK11 Q15759 2/20 0.51
RAF1 P04049 1/20 0.51
TEK Q02763 3/20 0.48
ALOX5 P09917 1/20 0.43
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
MGAM O43451 2/20 0.41
GAA P10253 2/20 0.41
SI P14410 2/20 0.41
MGAM2 Q2M2H8 2/20 0.41
GCGR P47871 1/20 0.40
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29258832 0.89 MAPK14 (0.52) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL29258472 0.82 MAPK14 (0.47) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28977872 0.82 MAPK14 (0.47) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL4632626 0.81 MAPK13 (0.45) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL29363034 0.79 TEK (0.70) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL942701 0.79 TEK (0.70) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL3454813 0.76 MAPK14 (0.71) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL14991080 0.76 MGAM (0.46) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL14648010 0.75 MAPK13 (0.52) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL11212515 0.74 MAPK13 (0.76) MAPK14MAPK13MAPK12MAPK11RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906271-B2 Photosensitive resin composition for color filter and color filter using the same CHEIL INDUSTRIES INC. (KR) 2014-12-09 US disclosed
US-8822110-B2 Photosensitive resin composition for color filter and color filter including the same CHEIL INDUSTRIES INC. (KR) 2014-09-02 US disclosed
US-20130143158-A1 Photosensitive Resin Composition for Color Filter and Color Filter Including the Same CHEIL INDUSTRIES INC. (KR) 2013-06-06 US disclosed
US-20130141810-A1 Photosensitive Resin Composition for Color Filter and Color Filter Using the Same CHEIL INDUSTRIES INC. (KR) 2013-06-06 US disclosed
EP-1589374-B1 Polymerizable composition and process for producing lithographic plate using the polymerizable composition FUJIFILM CORP (JP) 2008-10-01 EP disclosed