Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 5/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309612 | 0.87 | VCAM1 (0.55) | VCAM1MEN1KMT2AALDH1A1GRIN2D | |
| SCHEMBL14247533 | 0.79 | VCAM1 (0.47) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14247077 | 0.79 | VCAM1 (0.51) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1675905 | 0.77 | VCAM1 (0.44) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9899661 | 0.76 | VCAM1 (0.56) | VCAM1MEN1KMT2AMAOAMAOB | |
| SCHEMBL29833735 | 0.76 | TTR (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL1680932 | 0.76 | TTR (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL4167481 | 0.75 | VCAM1 (0.59) | VCAM1MEN1KMT2AMAOAMAOB | |
| SCHEMBL31159817 | 0.73 | ERN1 (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28302343 | 0.73 | GPR35 (0.47) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650353-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024149080-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | 中国科学院上海药物研究所 | 2024-07-18 | — | — | WO | disclosed |
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |