Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927236 | 0.88 | NAMPT (0.68) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258225 | 0.88 | NAMPT (0.68) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL30927201 | 0.87 | NAMPT (0.69) | NAMPTMEN1MAPTKMT2A | |
| SCHEMBL29258100 | 0.87 | NAMPT (0.69) | NAMPTMEN1MAPTKMT2A | |
| SCHEMBL29258086 | 0.86 | NAMPT (0.71) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258286 | 0.86 | MEN1 (0.56) | NAMPTCYP19A1HTTMEN1MAPT | |
| SCHEMBL30927215 | 0.86 | MEN1 (0.56) | NAMPTCYP19A1HTTMEN1MAPT | |
| SCHEMBL29258194 | 0.86 | NAMPT (0.68) | NAMPTHTTMEN1MAPTKMT2A | |
| SCHEMBL30927229 | 0.86 | NAMPT (0.68) | NAMPTHTTMEN1MAPTKMT2A | |
| SCHEMBL30927217 | 0.83 | NAMPT (0.69) | NAMPTCYP19A1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |