Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317601 | 0.85 | KMT2A (0.49) | SMN1; SMN2TSHRALDH1A1FFAR1CPA1 | |
| SCHEMBL7929513 | 0.85 | KMT2A (0.49) | SMN1; SMN2TSHRALDH1A1FFAR1CPA1 | |
| SCHEMBL6824207 | 0.85 | KMT2A (0.49) | SMN1; SMN2TSHRALDH1A1FFAR1CPA1 | |
| SCHEMBL3510081 | 0.82 | TSHR (0.47) | HTTSMN1; SMN2TSHRALDH1A1CTSB | |
| SCHEMBL19434515 | 0.81 | HTT (0.44) | HTTSMN1; SMN2TSHRALDH1A1NPC1 | |
| SCHEMBL29101924 | 0.81 | HTT (0.47) | HTTSMN1; SMN2TSHRALDH1A1FOLH1 | |
| SCHEMBL27129558 | 0.81 | TSHR (0.45) | HTTSMN1; SMN2TSHRALDH1A1CTSB | |
| SCHEMBL27032236 | 0.81 | TSHR (0.45) | HTTSMN1; SMN2TSHRALDH1A1CTSB | |
| SCHEMBL27032017 | 0.81 | TSHR (0.45) | HTTSMN1; SMN2TSHRALDH1A1CTSB | |
| SCHEMBL3512342 | 0.81 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2TSHRALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916225-A | N-heterocyclyl substituted 2-cyano-3- (naphthalen-2-yl) acrylamide derivatives as fluorophores for detection of amyloid and amyloid-like proteins for diagnosis of neurodegenerative disorders | 阿米达斯公司 | 2024-04-19 | — | — | CN | disclosed |