SCHEMBL6824207

SCHEMBL6824207

C[C@H](CC(=O)O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH1A1 P00352 3/20 0.48
CPA1 P15085 2/20 0.46
CPB1 P15086 1/20 0.46
CPA3 P15088 1/20 0.46
CPB2 Q96IY4 1/20 0.46
FFAR1 O14842 2/20 0.45
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
LTA4H P09960 2/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2317601 1.00 KMT2A (0.49) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL7929513 1.00 KMT2A (0.49) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL34471031 0.91 TSHR (0.45) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL2312535 0.87 ALDH1A1 (0.52) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL21536617 0.87 ALDH1A1 (0.52) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL18112934 0.86 SLC1A3 (0.44) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL20581847 0.86 ALDH1A1 (0.50) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL7507596 0.86 ALDH1A1 (0.50) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL29259157 0.85 HTT (0.44) ALDH1A1CPA1CPB1CPA3CPB2
SCHEMBL24335280 0.84 MMP1 (0.48) KMT2ASLC1A3SLC1A2SLC1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090272-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASE 2508 BIOSCIENCES LLC (US) 2026-04-30 WO disclosed
EP-3634430-B1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-08-07 EP disclosed
US-20240180941-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-06-06 US disclosed
US-11813272-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2023-11-14 US disclosed
US-20230293458-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2023-09-21 US disclosed
CN-109071467-B Acyclic antiviral agents 艾丽奥斯生物制药有限公司 2023-04-04 CN disclosed
US-11472826-B2 Acyclic antivirals JANSSEN PHARMACEUTICA NV (BE) 2022-10-18 US disclosed
US-20210177877-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2021-06-17 US disclosed
EP-3801496-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE Flagship Pioneering Innovations V, Inc. (US) 2021-04-14 EP disclosed
US-10953027-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2021-03-23 US disclosed
EP-3426642-A1 ACYCLIC ANTIVIRALS Alios Biopharma, Inc. (US) 2019-01-16 EP disclosed
CN-109071467-A Acyclic antiviral agent 艾丽奥斯生物制药有限公司 2018-12-21 CN disclosed
WO-2018226732-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2018-12-13 WO disclosed
WO-2017156262-A1 ACYCLIC ANTIVIRALS ALIOS BIOPHARMA, INC. (US) 2017-09-14 WO disclosed
US-6737416-B2 THROMBOLYTIC AGENT HAVING HIGHER SAFETY MEIJI SEIKA KAISHA LTD. (JP) 2004-05-18 US disclosed
US-20030119787-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B MEIJI SEIKA KAISHA LTD. (JP) 2003-06-26 US disclosed
US-6576627-B1 Such as 7-amino-2-((2-methyl-1-(3-phenylpropanoylamino)-propyl)hydroxyphosphinoyl) -methylheptanoic acid; thrombotic disease MEIJI SEIKA KAISHA LTD. (JP) 2003-06-10 US disclosed
EP-1152004-B1 Phosphonic acid derivatives having carboxypeptidase B inhibitory action MEIJI SEIKA KAISHA (JP) 2003-05-07 EP disclosed
EP-1174434-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B MEIJI SEIKA KAISHA LTD. (JP) 2002-01-23 EP disclosed
EP-1152004-A1 PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITORY ACTIVITY MEIJI SEIKA KAISHA LTD. (JP) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472826-B2 Acyclic antivirals PNP, DUT, TYMP KMT2A 2535/4885SLC1A3 1809/4885SLC1A2 2655/4885
US-20030119787-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B CPB1, RNPEP, CPN1 KMT2A 2641/4885SLC1A3 1337/4885SLC1A2 1615/4885
US-11813272-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FABP1, PYGL, LIPC KMT2A 3546/4885SLC1A3 2178/4885SLC1A2 1783/4885
US-20240180941-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FABP1, PYGL, LIPC KMT2A 3546/4885SLC1A3 2178/4885SLC1A2 1783/4885
US-20230293458-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME SI, FABP2, CEL KMT2A 1842/4885SLC1A3 2515/4885SLC1A2 3039/4885
US-20210177877-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FABP1, PYGL, LIPC KMT2A 3546/4885SLC1A3 2178/4885SLC1A2 1783/4885
US-10953027-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FABP1, PYGL, LIPC KMT2A 3546/4885SLC1A3 2178/4885SLC1A2 1783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.