Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 18/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439807 | 0.90 | GHSR (0.49) | GHSRMAPTNPSR1GAATHRB | |
| SCHEMBL29233311 | 0.88 | GHSR (0.49) | GHSR | |
| SCHEMBL25895788 | 0.85 | GHSR (0.49) | GHSR | |
| SCHEMBL29233309 | 0.84 | GHSR (0.55) | GHSR | |
| SCHEMBL30187446 | 0.82 | RORC (0.53) | GHSR | |
| SCHEMBL14863165 | 0.81 | GHSR (0.73) | GHSR | |
| SCHEMBL18940023 | 0.81 | MAPT (0.42) | GHSRMAPTNPSR1GAATHRB | |
| SCHEMBL18940138 | 0.80 | MAPT (0.42) | GHSRMAPTNPSR1GAATHRB | |
| SCHEMBL14744581 | 0.80 | ACE (0.56) | GHSR | |
| SCHEMBL18066415 | 0.80 | ACE (0.56) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580188-A | Can be used as ROR gamma regulator aniline compound (B) | 励缔(杭州)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-113773251-B | Anilines useful as rory modulators | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |