SCHEMBL29259176

SCHEMBL29259176

COC(=O)CC(C(=O)OC)C1CCCCC1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
KDM4E B2RXH2 2/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29235137 0.85 LMNA (0.36) LMNAKDM4EHTTSMN1; SMN2CYP2C19
SCHEMBL29053704 0.68 SLC6A3 (0.38) LMNAHTTCYP2D6TSHR
SCHEMBL11044234 0.68 SLC1A2 (0.34) KDM4EHTTSMN1; SMN2
SCHEMBL14563322 0.67 EPHX2 (0.38) LMNASMN1; SMN2EPHX2TDP1TSHR
SCHEMBL10136513 0.67 SLC1A2 (0.42) KDM4EHTTSMN1; SMN2TAAR1
SCHEMBL15592462 0.67 SLC1A2 (0.42) KDM4EHTTSMN1; SMN2TAAR1
SCHEMBL14447247 0.67 SLC1A2 (0.42) KDM4EHTTSMN1; SMN2TAAR1
SCHEMBL5513864 0.67 SLC1A2 (0.42) KDM4EHTTSMN1; SMN2TAAR1
SCHEMBL12868799 0.67 SLC1A2 (0.42) KDM4EHTTSMN1; SMN2TAAR1
SCHEMBL15774198 0.67 GLA (0.34) CYP2D6ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118186152-A Multifunctional high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-14 CN disclosed