SCHEMBL29259796

SCHEMBL29259796

COc1ccc(CCNS(=O)(=O)c2ccc(Br)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.86
SMN1; SMN2 Q16637 2/20 0.86
POLB P06746 1/20 0.74
PKM P14618 1/20 0.63
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA5A P35218 1/20 0.60
CA9 Q16790 1/20 0.60
CA14 Q9ULX7 1/20 0.60
EGFR P00533 1/20 0.60
ERBB2 P04626 1/20 0.60
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
AKR1C3 P42330 1/20 0.57
PPARG P37231 1/20 0.57
SGMS1 Q86VZ5 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7113122 0.93 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL11335294 0.87 ALDH1A1 (0.88) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL15619063 0.87 ALDH1A1 (0.88) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL29259801 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL10523408 0.86 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL10461753 0.86 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL10589292 0.86 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL6799293 0.86 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2POLBPKMCA12
SCHEMBL7109149 0.85 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2POLBPKMAKR1C3
SCHEMBL3914871 0.85 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2PKMEGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924125-A Method for preparing sulfonamide derivative through visible light catalysis without metal participation 苏州大学 2024-04-26 CN disclosed