Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | SNCA | P37840 | 9/20 | 0.53 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260651 | 1.00 | APP (0.53) | APPMAPTSNCAPARK7TDP1 | |
| SCHEMBL29260679 | 0.91 | APP (0.53) | APPMAPTSNCATDP1EP300 | |
| SCHEMBL29260681 | 0.91 | APP (0.53) | APPMAPTSNCATDP1EP300 | |
| SCHEMBL29260666 | 0.85 | CASP1 (0.52) | APPMAPTSNCACASP1CASP3 | |
| SCHEMBL29260669 | 0.85 | CASP1 (0.52) | APPMAPTSNCACASP1CASP3 | |
| SCHEMBL29260675 | 0.83 | TRPA1 (0.67) | APPMAPTSNCAPARK7CASP1 | |
| SCHEMBL29260673 | 0.83 | TRPA1 (0.67) | APPMAPTSNCAPARK7CASP1 | |
| SCHEMBL29260610 | 0.82 | MAPT (0.66) | APPMAPTSNCACASP1CASP3 | |
| SCHEMBL29260607 | 0.82 | MAPT (0.66) | APPMAPTSNCACASP1CASP3 | |
| SCHEMBL12930285 | 0.82 | TRPA1 (0.69) | APPMAPTSNCAPARK7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184701-A | Phosphono-substituted 3-methyleneoxindole compound and preparation and application thereof | 浙江工业大学 | 2024-06-14 | — | — | CN | disclosed |