Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892237 | 0.84 | CCNT1 (0.48) | CCNT1CDK9HPGDKDM4EHTR7 | |
| SCHEMBL31038587 | 0.82 | CCNT1 (0.39) | CCNT1CDK9HPGD | |
| SCHEMBL7706105 | 0.81 | KCNN4 (0.39) | ADRB2KCNN4KDM4EHTR7EGFR | |
| SCHEMBL29260764 | 0.80 | CCNT1 (0.37) | CCNT1CDK9PARP1PARP10PARP11 | |
| SCHEMBL30950381 | 0.80 | CCNT1 (0.37) | CCNT1CDK9PARP1PARP10PARP11 | |
| SCHEMBL7708733 | 0.79 | MAPT (0.38) | KCNN4EGFRL3MBTL1PTGS2BRD4 | |
| SCHEMBL31038547 | 0.73 | BTK (0.37) | CCNT1CDK9HTR7 | |
| SCHEMBL6048623 | 0.72 | KCNN4 (0.49) | HPGDADRB2KCNN4KDM4EHTR7 | |
| SCHEMBL7706809 | 0.69 | PTGS2 (0.34) | HPGDADRB2KCNN4KDM4EEGFR | |
| SCHEMBL29892345 | 0.67 | HPGD (0.54) | HPGDPARP1PDPK1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271300-A | Lactam compound, and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-07-02 | — | — | CN | disclosed |