Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706105 | 0.91 | KCNN4 (0.39) | KCNN4L3MBTL1EGFRPTGS2PTPN1 | |
| SCHEMBL678904 | 0.83 | L3MBTL1 (0.51) | MAPTL3MBTL1BRD4PTGS2MEN1 | |
| SCHEMBL6433580 | 0.82 | EGFR (0.37) | L3MBTL1EGFRMEN1KMT2A | |
| SCHEMBL11114109 | 0.81 | L3MBTL1 (0.50) | MAPTL3MBTL1BRD4POLB | |
| SCHEMBL7706809 | 0.81 | PTGS2 (0.34) | MAPTKCNN4EGFRPTGS2 | |
| SCHEMBL29260754 | 0.79 | CCNT1 (0.40) | KCNN4L3MBTL1EGFRBRD4PTGS2 | |
| SCHEMBL11113086 | 0.78 | ALDH1A1 (0.49) | BRD4MEN1KMT2APTPN1 | |
| SCHEMBL23645209 | 0.78 | MAPT (0.39) | MAPTL3MBTL1BRD4PTGS2 | |
| SCHEMBL23644257 | 0.76 | MAPT (0.37) | MAPTL3MBTL1BRD4POLBPTGS2 | |
| SCHEMBL6048623 | 0.75 | KCNN4 (0.49) | MAPTKCNN4L3MBTL1EGFRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |