Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664276 | 0.81 | ALDH1A1 (0.37) | KDM4CALDH1A1HPGDCA1CA2 | |
| SCHEMBL15093627 | 0.79 | ACLY (0.40) | KDM4CALDH1A1HPGDKDM5APARP1 | |
| SCHEMBL31056256 | 0.79 | AKR1C3 (0.42) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4C | |
| SCHEMBL2424869 | 0.79 | AKR1C3 (0.42) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4C | |
| SCHEMBL15093877 | 0.76 | PARP1 (0.44) | CYP3A4KDM4CALDH1A1HPGDHSD17B10 | |
| SCHEMBL2936494 | 0.76 | CYP3A4 (0.38) | DYRK1ACYP3A4KDM4CALDH1A1KDM5A | |
| SCHEMBL2919938 | 0.74 | CYP3A4 (0.46) | CYP3A4ALDH1A1TP53CA1CA2 | |
| Hydrochloric Acid SCHEMBL20562251 | 0.74 | PARP1 (0.43) | CYP3A4KDM4CALDH1A1HPGDHSD17B10 | |
| SCHEMBL20471835 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HSD17B10PARP1 | |
| SCHEMBL19612178 | 0.72 | AKR1C4 (0.42) | DYRK1AAKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084798-A | Synthesis method of 5-chloro-1H-benzimidazole-7-carboxylic acid | 南通大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084798-A | Synthesis method of 5-chloro-1H-benzimidazole-7-carboxylic acid | 南通大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084798-A | Synthesis method of 5-chloro-1H-benzimidazole-7-carboxylic acid | 南通大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084798-A | Synthesis method of 5-chloro-1H-benzimidazole-7-carboxylic acid | 南通大学 | 2024-05-28 | — | — | CN | disclosed |