Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 20/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.49 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262514 | 1.00 | ADAMTS5 (0.49) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL23745416 | 0.81 | ADAMTS5 (0.61) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL29262532 | 0.81 | ADAMTS5 (0.51) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL29262554 | 0.81 | ADAMTS5 (0.51) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL31121189 | 0.79 | ADAMTS5 (0.64) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL23745359 | 0.79 | ADAMTS5 (0.64) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL23745439 | 0.72 | ADAMTS5 (0.53) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL23728103 | 0.72 | ADAMTS5 (0.53) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL30899243 | 0.72 | ADAMTS5 (0.53) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 | |
| SCHEMBL23745240 | 0.72 | ADAMTS5 (0.53) | ADAMTS5ADAM17MMP2MMP14ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754635-B | Condensed ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-113754635-A | Fused ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2021-12-07 | — | — | CN | disclosed |