SCHEMBL29263263

SCHEMBL29263263

FC(F)(F)c1cc(-c2cc3ccccc3s2)nc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.54
ACP1 P24666 3/20 0.41
CYP19A1 P11511 1/20 0.40
KDM1A O60341 2/20 0.40
NQO1 P15559 1/20 0.40
NQO2 P16083 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
APP P05067 2/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
PIK3CG P48736 1/20 0.37
KCNH2 Q12809 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
RXFP1 Q9HBX9 2/20 0.36
TMIGD3 P0DMS9 1/20 0.36
ADORA1 P30542 1/20 0.36
STAT1 P42224 1/20 0.36
CASP3 P42574 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31023423 1.00 BACE1 (0.54) BACE1ACP1CYP19A1KDM1ANQO1
SCHEMBL6534342 0.78 MEN1 (0.45) ACP1CYP19A1KDM1ANQO1NQO2
SCHEMBL24702704 0.77 KDM1A (0.40) ACP1CYP19A1KDM1ANQO1NQO2
SCHEMBL31038115 0.72 RAB9A (0.54) BACE1CYP19A1KDM1ANQO1NQO2
SCHEMBL2208526 0.72 RAB9A (0.54) BACE1CYP19A1KDM1ANQO1NQO2
SCHEMBL4116547 0.71 BACE1 (1.00) BACE1ACP1NQO2KCNH2KMT2A
SCHEMBL19961704 0.71 RAB9A (0.59) CYP19A1APPMEN1KMT2ARXFP1
SCHEMBL29386742 0.71 RAB9A (0.59) CYP19A1APPMEN1KMT2ARXFP1
SCHEMBL12383603 0.70 NQO1 (0.45) CYP19A1KDM1ANQO1NQO2APP
SCHEMBL28380347 0.70 NQO1 (0.49) CYP19A1KDM1ANQO1NQO2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126090-A Iridium complex photosensitizer and preparation method and application thereof 南京工业大学 2024-06-04 CN claimed
CN-118126090-A Iridium complex photosensitizer and preparation method and application thereof 南京工业大学 2024-06-04 CN disclosed