SCHEMBL2926353

SCHEMBL2926353

CCCCCCCC/C=C\CCCCCCCC(CCCCCCCC)OC(=O)C(O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.50
FFAR4 Q5NUL3 1/20 0.50
GPR84 Q9NQS5 4/20 0.47
TERT O14746 3/20 0.47
PTPN1 P18031 3/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
TOP1 P11387 3/20 0.47
MAPT P10636 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
POLB P06746 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10534358 1.00 FFAR1 (0.50) FFAR1FFAR4GPR84TERTPTPN1
SCHEMBL9784172 0.94 FFAR1 (0.51) FFAR1FFAR4TERTPTPN1PPARG
SCHEMBL9784063 0.94 FFAR1 (0.51) FFAR1FFAR4TERTPTPN1PPARG
SCHEMBL23361766 0.91 GPR84 (0.56) FFAR1FFAR4GPR84MAPTBLM
SCHEMBL2231103 0.91 GPR84 (0.56) FFAR1FFAR4GPR84MAPTBLM
SCHEMBL6374127 0.91 GPR84 (0.56) FFAR1FFAR4GPR84MAPTBLM
SCHEMBL9784116 0.91 GPR84 (0.56) FFAR1FFAR4GPR84MAPTBLM
SCHEMBL10534356 0.89 PRKCA (0.50) FFAR1FFAR4MAPTFAAH
SCHEMBL2926352 0.89 PRKCA (0.50) FFAR1FFAR4MAPTFAAH
SCHEMBL25182618 0.84 GPR84 (0.50) FFAR1FFAR4GPR84MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1078977-B1 LUBRICANT COMPOSITIONS AFTON CHEMICAL LTD (GB) 2010-01-27 EP disclosed
EP-0978554-B1 Turbine and R&O oils containing neutral rust inhibitors ETHYL PETROLEUM ADDITIVES LTD (GB) 2003-12-17 EP disclosed
US-6326336-B1 MIXTURE CONTAINING ANTIOXIDANT ETHYL CORPORATION 2001-12-04 US disclosed
EP-1078977-A1 LUBRICANT COMPOSITIONS ETHYL PETROLEUM ADDITIVES LIMITED (GB) 2001-02-28 EP disclosed
EP-0994175-A2 Turbine oils with excellent high temperature oxidative stability ETHYL CORPORATION (US) 2000-04-19 EP disclosed
EP-0978554-A2 Turbine and R&O oils containing neutral rust inhibitors ETHYL PETROLEUM ADDITIVES LIMITED (GB) 2000-02-09 EP disclosed