Leucine — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	SLC7A5	Q01650	2/20	0.53

▸	SLC1A2	P43004	7/20	0.44

▸	SLC1A3	P43003	6/20	0.44

▸	NOS1	P29475	2/20	0.43

▸	NOS3	P29474	1/20	0.43

▸	NOS2	P35228	1/20	0.43

▸	SLC1A1	P43005	6/20	0.41

▸	GRIK1	P39086	4/20	0.36

▸	GRIK2	Q13002	3/20	0.36

▸	CTSS	P25774	1/20	0.35

▸	CTSK	P43235	1/20	0.35

▸	LAP3	P28838	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Leucine SCHEMBL29264279	0.97	SLC7A5 (0.50)	SLC7A5SLC1A2SLC1A3NOS1NOS3
SCHEMBL919004	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
SCHEMBL1952051	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
SCHEMBL1952544	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
SCHEMBL1841059	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
SCHEMBL4425446	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
SCHEMBL6224216	0.86	NOS1 (0.53)	NOS1NOS3NOS2CTSSCTSK
Acetic Acid SCHEMBL9342261	0.84	NOS1 (0.49)	NOS1NOS3NOS2CTSSCTSK
Hydrochloric Acid SCHEMBL954680	0.84	NOS1 (0.51)	NOS1NOS3NOS2CTSSCTSK
Hydrochloric Acid SCHEMBL919002	0.84	NOS1 (0.51)	NOS1NOS3NOS2CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118215474-A	Methods and compositions for weight management	爱医谷(苏州)生物科技有限公司	2024-06-18	—	—	CN	disclosed