SCHEMBL919004

SCHEMBL919004

CC[C@H](C)[C@H](N)C(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.53
NOS3 P29474 1/20 0.53
NOS2 P35228 1/20 0.53
DPP4 P27487 14/20 0.41
DPP8 Q6V1X1 8/20 0.41
DPP9 Q86TI2 7/20 0.41
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
DPP7 Q9UHL4 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6224216 1.00 NOS1 (0.53) NOS1NOS3NOS2DPP4DPP8
SCHEMBL1952544 1.00 NOS1 (0.53) NOS1NOS3NOS2DPP4DPP8
SCHEMBL4425446 1.00 NOS1 (0.53) NOS1NOS3NOS2DPP4DPP8
SCHEMBL1952051 1.00 NOS1 (0.53) NOS1NOS3NOS2DPP4DPP8
SCHEMBL1841059 1.00 NOS1 (0.53) NOS1NOS3NOS2DPP4DPP8
Hydrochloric Acid SCHEMBL954680 0.98 NOS1 (0.51) NOS1NOS3NOS2DPP4DPP8
Hydrochloric Acid SCHEMBL919003 0.98 NOS1 (0.51) NOS1NOS3NOS2DPP4DPP8
Hydrochloric Acid SCHEMBL919002 0.98 NOS1 (0.51) NOS1NOS3NOS2DPP4DPP8
Acetic Acid SCHEMBL9342261 0.94 NOS1 (0.49) NOS1NOS3NOS2DPP4DPP8
Leucine SCHEMBL29264283 0.86 SLC7A5 (0.53) NOS1NOS3NOS2CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163507-B Recombinant antigen protein rP44-60 for detecting granulocytoplasmatic disease and kit containing antigen 河套学院 2023-06-20 CN claimed
CN-114163507-A Recombinant antigen protein rP44-60 for detecting granulocytic anaplasmosis and kit containing antigen 河套学院 2022-03-11 CN claimed
CN-110269858-B Twin medicine for treating ischemic stroke and preparation method thereof 贵州医科大学 2021-07-09 CN claimed
EP-4733307-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-29 EP disclosed
CN-119841841-A Cycloicaritin carbamate prodrug and salt thereof 沈阳药科大学 2025-04-18 CN disclosed
EP-4538279-A2 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2025-04-16 EP disclosed
WO-2025070753-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE 中外製薬株式会社 2025-04-03 WO disclosed
US-20240425512-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF 280 BIO, INC. (US) 2024-12-26 US disclosed
WO-2024254404-A2 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF 280 BIO, INC. (US) 2024-12-12 WO disclosed
CN-119101070-A Nitrogen-containing heterocyclic compound, pharmaceutical composition and application thereof 上海璎黎药业有限公司 2024-12-10 CN disclosed
US-12122742-B2 Small molecule direct inhibitors of KEAP1-NRF2 protein-protein interaction RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-10-22 US disclosed
WO-1998006386-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM ROCHE DIAGNOSTICS GMBH (DE) 1998-02-19 WO disclosed
WO-1998005625-A1 DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY BRACCO S.P.A. (IT) 1998-02-12 WO disclosed
US-5668291-A THIOSUBSTITUTED PYRIDINES, TREATMENT OF AIDS AND HIV WARNER-LAMBERT COMPANY (US) 1997-09-16 US disclosed
US-5668162-A Isothiazolones lower plasma levels of lipoprotein(a) WARNER-LAMBERT COMPANY 1997-09-16 US disclosed
EP-0775110-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1997-05-28 EP disclosed
US-5620997-A VIRICIDES, ANTIINFLAMMATORY AGENTS, ANTIATHEROSCLEROTIC AGENT WARNER-LAMBERT COMPANY (US) 1997-04-15 US disclosed
WO-1996038144-A1 ISOTHIAZOLONES WARNER-LAMBERT COMPANY (US) 1996-12-05 WO disclosed
WO-1996004242-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1996-02-15 WO disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425512-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF KRAS, NRAS, HRAS NOS1 407/4885NOS3 465/4885NOS2 704/4885
US-12122742-B2 Small molecule direct inhibitors of KEAP1-NRF2 protein-protein interaction KEAP1, NFE2L2, HMOX1 NOS1 261/4885NOS3 397/4885NOS2 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.